Abstract Categories: 20. M1) Extracorporeal dialysis: techniques and adequacy Keywords: haemodialysis: technique, liver, calcium, haemodialysis: outcome Title: Citrate Dialysate in Advanced Liver Failure

INTRODUCTION AND AIMS: Citrate dialysate (CD) has been safely used for both acute and chronic dialysis. It has also been reported to be safe for use in both traditional intermittent and Slow Low Efficiency Diffusion Dialysis (SLEDD) in acutely ill patients. However, since the liver is a major site of citrate metabolism the safety of CD in liver failure patients needs to be evaluated. At University of Washington CD is routinely used for heparin free dialysis. The aim of this study was to assess the safety and efficacy of CD used for SLEDD in the presence of severe liver failure.